ER-positive breast cancer cells are poised for RET-mediated endocrine resistance.
The RET tyrosine kinase signaling pathway is involved in the development of endocrine resistant ER+ breast cancer.However, we know little about how ER+ cells activate RET signaling and initiate an endocrine resistant phenotype.Here 2.5" Squares (Mini Charms) we show that both ER+ endocrine resistant and sensitive breast cancers have a functional RE